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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITPNA
All Species:
40.61
Human Site:
T222
Identified Species:
99.26
UniProt:
Q00169
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00169
NP_006215.1
270
31806
T222
K
Q
E
R
R
L
F
T
N
F
H
R
Q
L
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101197
272
31620
T222
K
Q
E
K
R
I
F
T
N
F
H
R
Q
L
F
Dog
Lupus familis
XP_537767
353
40687
T305
K
Q
E
R
R
L
F
T
N
F
H
R
Q
L
F
Cat
Felis silvestris
Mouse
Mus musculus
P53810
271
31875
T223
K
Q
E
K
R
L
F
T
N
F
H
R
Q
L
F
Rat
Rattus norvegicus
P16446
271
31889
T223
K
Q
E
K
R
L
F
T
N
F
H
R
Q
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518945
264
30788
T216
K
Q
E
K
R
L
F
T
N
F
H
R
Q
L
F
Chicken
Gallus gallus
XP_001234813
858
98308
T229
K
Q
E
K
R
L
F
T
N
F
H
R
Q
L
F
Frog
Xenopus laevis
NP_001086964
271
31542
T222
K
Q
E
K
R
I
F
T
N
F
H
R
Q
V
F
Zebra Danio
Brachydanio rerio
XP_002663601
270
31813
T221
K
Q
E
K
R
L
F
T
N
F
H
R
Q
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624564
271
31530
T223
K
A
E
R
R
L
F
T
N
F
H
R
Q
V
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.8
74.5
N.A.
98.5
98.8
N.A.
84.8
28.4
75.2
83.3
N.A.
N.A.
61.9
N.A.
N.A.
Protein Similarity:
100
N.A.
88.5
74.7
N.A.
99.6
99.6
N.A.
89.6
30.1
88.5
92.9
N.A.
N.A.
77.4
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
100
N.A.
93.3
93.3
N.A.
93.3
93.3
80
93.3
N.A.
N.A.
86.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
100
0
0
100
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
100
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
80
0
0
0
0
0
0
0
80
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
90
0
0
0
0
0
0
0
0
0
0
100
0
0
% Q
% Arg:
0
0
0
30
100
0
0
0
0
0
0
100
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _